Ukuhlolwa Kwasekhaya Kwe-COVID-19 Antigen: Okufanele Ukwazi

I-Wirecutter isekela abafundi.Uma uthenga ngesixhumanisi esikuwebhusayithi yethu, singathola ikhomishana esebenzisana nayo.Funda kabanzi
Ngokuhlolwa okunobungozi obuphansi be-COVID-19, ukuhlolwa kwe-antigen okusheshayo kunikeza indlela esheshayo nelula yokuhlolela i-SARS-CoV-2 ekhaya.Ziwusizo ikakhulukazi uma wazi noma usola ukuthi uke wachayeka ku-coronavirus kodwa awukwazi ukuthola ukuhlolwa kochwepheshe (noma ulinde imiphumela).
Ukuhlola okugunyazwe yi-FDA kwe-antigen yasekhaya kungathola ukutheleleka okusebenzayo kwe-COVID-19, okuhlanganisa abantu abangenazimpawu, emizuzwini eyi-15.Sekukonke, lokhu kuhlolwa akuzweli njengokuhlolwa kwamangqamuzana okwenziwa ezindaweni zokucwaninga.Noma kunjalo, imiphumela yokuhlolwa kwe-antigen yasekhaya inganikeza idatha eyengeziwe—uma ingakhululekanga ngokuphelele—mayelana nesimo somuntu se-COVID-19, ikakhulukazi uma uhlola njalo.Kuye ngesimo sakho, kungase kube nengqondo ukuba nezinye zalezi zivivinyo esandleni.
Khumbula, umphumela ongemuhle awusho ngempela ukuthi othile akanayo i-COVID-19, futhi lokhu kuhlola akwenzelwe ukuthi kusetshenziswe njengendlela yokuhlola kuphela.UDkt. Matthew McCarthy, oyisekela likaprofesa wezokwelapha e-Weill Cornell School of Medicine, uthe: “Ukuhlolwa kwe-antigen kuyindlela eshibhile nelula yokuhlonza abantu okungenzeka banezifo.”Kubantu abangenawo umlando owaziwayo wokuchayeka ku-COVID-19, “uma uya e-Thanksgiving, lapho kunabantu abangu-20 futhi bonke begonyiwe, ungenza ukuhlolwa kwe-antigen ngaphambi kokuthi uhambe ukuze uqiniseke ukuthi awuzange ulethe leli gciwane. iqembu,” usho kanje, ecaphuna okungase kusetshenziswe.
Kungase futhi kufaneleke ukwenza ukuhlola okusheshayo kwe-antigen ngaphambi kokuxhumana nabantu abangase bangenwe kalula yigciwane.UDkt. Claire Rock, udokotela wezifo eziwumshayabhuqe e-Johns Hopkins University School of Medicine, uthe: “Ngisho nabantu abagonywe ngokuphelele bangase bafune ukuthatha enye yalezi zivivinyo ezilula zasekhaya ngaphambi kokuchitha isikhathi nogogo,” ophethe inkampani yokubonisana nokulawula ukutheleleka nge-COVID-19. .
Ukuhlolwa kwe-COVID-19 antigen ekhaya kungaba lula futhi kusheshe.Asikho isidingo sokulinda i-aphoyintimenti (noma u-ode ikhithi ngeposi nangomkhumbi amasampula) bese ulinda imiphumela yokuhlolwa kokuxilonga kwamangqamuzana.Ngokwenza ukuhlolwa kwe-antigen ekhaya, ngokuvamile ungathatha imizuzu engu-15 ukusuka ku-swab kuya kumphumela.Lezi zivivinyo ngokuvamile kulula ukuzenza, futhi ungafunda imiphumela mathupha (njengokusebenzisa ukuhlolwa kokukhulelwa kwasekhaya) noma ngedijithali (usebenzisa uhlelo lokusebenza).
Ukuhlolwa kwe-COVID-19 antigen akuzwela njengokuxilongwa kwamangqamuzana.Ngokungafani nokuhlolwa kokuxilonga kwamangqamuzana e-COVID-19, okubandakanya ukukhulisa i-viral nucleic acid ibe sezingeni okulula ukulithola, ukuhlolwa kwe-antigen kungathola iminonjana yegciwane elingakhulisiwe, ngakho akulula ukuthola amasiginali amancane.(Ungaphambanisi ukuhlolwa kwe-antigen nokuhlolwa kwe-antibody. Ukuhlolwa kwe-antibody kuklanyelwe ukuthola amasosha omzimba asabela egciwaneni futhi akusetshenziselwa izinjongo zokuxilonga.)
Yize ukuhlolwa kwe-antigen yasekhaya kungekona okungenangqondo, lapho kuthola amacala e-COVID-19 asebenzayo, ngisho nezindlela zokuxilonga zamangqamuzana njengokuhlola kwegolide okujwayelekile kwe-PCR azihlali zinembile, ngoba imiphumela incike, phakathi kwezinye izinto, esikhathini sokuhlolwa..Uma usule ngaphambi kwesikhathi ngemva kokuxhumana, umphumela wakho wokuhlolwa ungase ube negethivu ngisho noma unegciwane.Ngemuva kokuthi ungasatheleli, ungaphinda uthole umphumela wokuhlola we-PCR.
Udokotela wezifo eziwumshayabhuqe emtholampilo u-Rock uthe uma kuqhathaniswa nokuxilongwa kwamangqamuzana e-COVID-19, ukuhlolwa kwe-antigen “akuzweli kangako uma sifuna ukwazi ukuthi akhona yini amagciwane amancane, kodwa uma siwafuna, azwela kakhulu” bheka Ukuze ubone. uma kunezinga elithile legciwane, kumelwe sikhathazeke ngokuthi othile uzothelela abanye.”

"Sivame ukutusa ukuhlola izinsuku ezintathu kuya kwezinhlanu ngemva kokuchayeka." - UDkt.Matthew McCarthy, Weill Cornell School of Medicine
Ukunemba kokuhlolwa kwe-antigen yasekhaya kuncike ngokwengxenye ekuzweleni kokuhlolwa (ikhono lombiko wokuhlola ukuthola amaphuzu ayiqiniso), ukucaciswa kokuhlolwa (ikhono lombiko lokuthola ama-negative wangempela), kanye nobuqotho besampula ( noma ngabe i-swab iqukethe amasampula anele noma ama-swabs Isixazululo singcoliswe enye i-pathogen), kungakhathaliseki ukuthi imiyalelo yomkhiqizi ilandelwe ngokugcwele, isikhathi kusukela ekuthinteni kokugcina okwaziwayo noma okusolwayo kanye/noma ukuqala kwezimpawu, kanye nomthamo wegciwane egazini isikhathi sokuhlolwa.(Okwamanje lokhu kuhlola kugunyazwe abantu abaneminyaka engu-2 ubudala, inqobo nje uma noma imaphi amasampula ezingane atholwa futhi acutshungulwe abantu abadala.)
Ngokuhlolwa okucatshangelwe ukugunyazwa kokusetshenziswa okuphuthumayo, umenzi wokuhlola kufanele athumele idatha yomtholampilo ku-FDA ukuze abonise ukuzwela nokucaciswa kokuhlolwa.Ezinye izifundo ezizimele zibonise ukuthi ukuzwela nokucaciswa kokuhlolwa okuthile kwe-antigen kuphansi kakhulu, ikakhulukazi uma kusetshenziswa kubantu abangenazimpawu.(Okwamanje kunokuhlolwa kokuxilonga kwamangqamuzana e-SARS-CoV-2 okudayiswayo okugunyazwe yi-FDA futhi kungasetshenziswa ekhaya ukuze kusetshenziswe izimo eziphuthumayo, okusho ukuthi awudingi ukuthumela amasampula elabhorethri ukuze ahlolwe: Lucira COVID -19 All- In-One Test Kit. Uma iqhathaniswa nokuhlola okugunyazwe yi-FDA kwe-antigen yasekhaya, inokuzwela okungaphezulu kancane (95.2%) futhi inganikeza imiphumela phakathi nemizuzu engama-30. Nokho, okwamanje ayitholakali kuwebhusayithi kaLucira ne-Amazon. kanye.)
Ngesikhathi sokushicilela, bekunzima ukuthola izivivinyo ze-antigen yasekhaya ngoba ukwanda kwamacala e-COVID-19 kuholele ekufuneni kwawo.Uma ungakwazi ukuzithola ku-inthanethi, sicela ushayele ikhemisi langakini (lokhu kuhlolwa kuvame ukutholakala edeskini elingaphambili).
I-Abbott BinaxNow COVID-19 antigen self-test sensitivity: 84.6% (PDF) (ezinsukwini eziyi-7 ngemuva kokuqala kwezimpawu) Ukucaciswa: 98.5% (PDF) (ezinsukwini eziyi-7 ngemuva kokuqala kwezimpawu) Ukuhlolwa kuhlanganisa: izindleko ezimbili: $24 Ukutholakala: Amazon, CVS, Walmart
Ukuhlolwa kwekhaya kwe-Ellume COVID-19 (kudingeka isicelo) Ukuzwela: 95% (PDF) Ukucaciswa: 97% (PDF) Ukuhlolwa kuhlanganisa: 1 Izindleko: $35 Ukutholakala: Amazon, CVS, Target
Ukuzwela Kokuhlolwa Kwekhaya Le-Quidel QuickVue I-COVID-19: 84.8% (PDF) Ukucaciswa: 99.1% (PDF) Ukuhlolwa kuhlanganisa: izindleko ezimbili: $25 Ukutholakala: Amazon, Walmart
Ukhiye wokuthola imiphumela yokuhlolwa kwe-antigen enokwethenjelwa ukuhlola okuvamile."Ukuhlola okuqhubekayo kungakhulisa ukuzwela," kusho uChristoper Brooke, uchwepheshe wezifo ezithathelwanayo e-University of Illinois e-Urbana-Champaign."Amathuba okuhlolwa okubili okungenayo ngemuva kokutheleleka aphansi kakhulu kunamathuba okuhlolwa okukodwa okungenayo."
Ukuhlolwa kwe-antigen yasekhaya kwe-Abbott, Ellume kanye ne-Quidel akudingi ukuthi i-swab iphushelwe ku-nasopharyngeal cavity, ongase uhlangane nayo endaweni yokuhlolwa komtholampilo, kodwa idinga i-swab yamakhala emaphakathi engena kancane.Ukuhlolwa ngakunye kuneziyalezo eziqondile futhi ngokuyisisekelo kudinga ukuthi usule ikhala lakho, ucwilise i-swab esixazululweni, udlulisele esinye sesixazululo esitsheni esincane, bese ulinda umphumela.
Ngemva kwemizuzu engaba ngu-15, ungafunda imiphumela yokuhlolwa kwe-Abbott BinaxNow ne-Quidel QuickVue, njengokufunda ukuhlolwa kokukhulelwa kwasekhaya: imigqa emibili ikhombisa imiphumela emihle kanye nomugqa owodwa (ukulawula) ukhombisa imiphumela engemihle.Umugqa wesibili ofile kakhulu usengakhombisa umphumela omuhle.Ukuhlolwa kwasekhaya kwe-Ellume COVID-19 kudinga uxhumano lwe-Bluetooth kumakhalekhukhwini ukuze kunikezwe imiphumela phakathi nemizuzu engu-15 ngohlelo lokusebenza oluhambisanayo (i-iOS, Android).Ngokomgomo wobumfihlo wenkampani, u-Ellume kufanele anikeze iziphathimandla zezempilo yomphakathi usuku lokuzalwa lomsebenzisi nesimo sakhe salapho ahlala khona nekhodi yeposi, imiphumela yokuhlolwa, usuku lwemiphumela yokuhlolwa, nolunye ulwazi olungase lube khona oludingwa ngumthetho.
Njengazo zonke izifo zokuxilonga i-COVID-19 (okuhlanganisa nokuhlolwa kwe-PCR), isikhathi sokuqoqwa kwamasampula okokugcina okwaziwayo noma okusolisayo kanye/noma ukuqala kwezimpawu kuyisici esikhulu esithinta ukunemba kwemiphumela yokuhlolwa kwe-antigen yasekhaya.Isibonelo, yingakho i-Abbott's BinaxNOW kanye neQuidel's QuickVue test suites eza nokuhlola okubili okuklanyelwe ukusetshenziswa izinsuku ezimbili kuya kwezintathu ngokuhlukana.
"Ukuzwela kokuhlolwa kuncike ekutheni uyisebenzisa nini," kusho uDaniel Larremore, uprofesa osizayo wesayensi yamakhompiyutha eNyuvesi yaseColorado eBoulder, owasebenzisa ukuhlolwa kwamangqamuzana nama-antigen ukuze alingise imiphumela yokuhlolwa okuphindaphindiwe kubantu abangenazimpawu.Inani legciwane egazini lomuntu onaleli gciwane liyashintsha ngokuhamba kwesikhathi."Lapho ufinyelela inani legciwane eliphakeme ngokwanele, ukugcwala kwe-antigen kuzoba phezulu ngokwanele ukuze kuhlolwe."Ukuzihlola wena ngokwakho ngosuku olungemva kokuhambela iphathi nomuntu obengazi ukuthi une-COVID-19 ngaleso sikhathi mancane amathuba okuthi kube usizo."Akukho ukuhlolwa okuzoba nethemba amahora angama-24 ngemuva kokuchayeka," kusho uLarremore.Uma ulinda isikhathi eside kakhulu ukuze uhlolwe, ungase uphuthelwe ukugcwala okuphezulu kwe-antigen, okusho ukuthi uma ukuhlolwa kuthola i-antigen ye-SARS-CoV-2 kusampula yakho, kufanele ubone umugqa oqondile omnyama.
"Sivame ukuncoma ukuhlolwa kwezinsuku ezintathu kuya kwezinhlanu ngemuva kokuchayeka," kusho uMcCarthy wase-Weill Cornell University.Uma unezimpawu ezifana ne-COVID-19, awudingi ukulinda ukuhlolwa.
Uma ungaqiniseki noma udidekile mayelana nemiphumela yokuhlolwa kwe-antigen yasekhaya ye-COVID-19, sicela uthintane nodokotela wakho.Ukuthi kufanele ufune ukuhlolwa kwamangqamuzana okuqinisekisa kuncike esimweni sakho.U-Larremore uthe abantu kufanele baphathe umphumela wokuhlolwa we-antigen omuhle njengomphumela wangempela, ikakhulukazi uma ezinye izici (njengokuchayeka okungenzeka noma ukuvela kwezimpawu) zisekela umphumela.Lokhu kusho ukuhlukaniswa, ukuxwayisa noma yibaphi abathintwayo, futhi ngokunokwenzeka nokufuna izivivinyo zaselabhorethri ukuze kuqinisekiswe imiphumela.Funa ukwelashwa kwezimpawu njengoba kudingeka.NgokukaMcCarthy wase-Weill Cornell, uma othile enezinga eliphansi lokusola nge-COVID-19 (ngokwesibonelo, akanazimpawu, akagonyiwe, futhi/noma akanakho ukuchayeka okwaziwayo).
Ukuthola ukuhlolwa kwe-PCR okwenziwa ilabhorethri kuyindlela engcono kakhulu yokuhlonza i-COVID-19 ngokunembile, kodwa kungase kube nzima ukuthola isikhathi sokubonana, futhi ngezinye izikhathi “kuthatha isikhathi eside ukuthola imiphumela, kodwa imiphumela iyize,” kusho uBrooke. we-American University.Illinois.“Ngokufanelekile, wonke umuntu uzokwenza izivivinyo ze-PCR njalo futhi abike imiphumela ngokushesha, kodwa ngokusobala lokhu akunakwenzeka.Ukuhlolwa kwe-antigen ngokuvamile kuwukuphela kwenketho esebenza ngempela, ngakho-ke kungadlala indima ekwandiseni imvamisa kanye nobubanzi bokuhlolwa kuso sonke isibalo sabantu.Indima ebaluleke kakhulu.”
Imaski yendwangu “engcono kakhulu” yileyo ongayigqoka (hhayi ingxabano).Nansi indlela yokuthola imaski elingana, ehlunga kahle futhi ekhululekile.
Imaski engcono kakhulu yezingane yileyo ezizoyigqoka futhi zihlale ziyigqokile.Sincoma imikhiqizo eyisithupha enethezekile, ephefumulayo futhi elungele yonke iminyaka.
Imaski exekethile ingabangela ukugcwala kwezibuko.Uma ungafuni ukunamathisela ingaphezulu lemaski ebusweni bakho, ukuconsa okuvimbela inkungu kungasiza.(Kanjalo kungaba insipho noma amathe.)


Isikhathi sokuthumela: Sep-17-2021